100 Examples of sentences containing the common noun "kinase"

Definition

Kinase (noun) refers to a type of enzyme that catalyzes the transfer of phosphate groups from high-energy donor molecules, such as ATP, to specific substrates, which can include proteins, lipids, and carbohydrates. This process is critical in regulating various cellular functions, including metabolism, signaling, and cell division.

Synonyms

• Phosphotransferase
• Enzyme
• Biocatalyst

Antonyms

• Phosphatase (an enzyme that removes phosphate groups)
• Inhibitor (a substance that decreases enzyme activity)

Examples

1. The kinase activated the metabolic pathway.
2. Researchers found that the kinase plays a role in cell signaling.
3. Inhibiting the kinase could have therapeutic effects.
4. The new drug targets a specific kinase involved in cancer progression.
5. Scientists are studying how the kinase interacts with other proteins.
6. The kinase was isolated for further analysis.
7. During the experiment, the kinase activity increased significantly.
8. Mutations in the kinase gene can lead to various diseases.
9. The kinase phosphorylates the target protein efficiently.
10. Their findings suggest that the kinase is crucial for cell survival.
11. The kinase was overexpressed in the cancer cells.
12. The team used a fluorescent marker to visualize the kinase.
13. The role of the kinase in apoptosis is well documented.
14. Different types of kinase exist, each serving unique functions.
15. The kinase assay showed promising results in drug development.
16. Researchers aim to inhibit the kinase to stop tumor growth.
17. The kinase cascade is vital for signal transduction.
18. The study focused on a novel kinase implicated in diabetes.
19. The kinase domain was characterized using X-ray crystallography.
20. The kinase is responsible for the phosphorylation of serine residues.
21. The activation of the kinase is tightly regulated within the cell.
22. They discovered that the kinase could also act as a transcription factor.
23. The kinase pathway is a target for many cancer therapies.
24. Inhibitors of the kinase are being tested in clinical trials.
25. The research highlighted the importance of the kinase in inflammation.
26. The kinase regulates gene expression through phosphorylation.
27. Understanding the kinase structure could lead to new drug discoveries.
28. The kinase was found to interact with multiple signaling pathways.
29. The effects of the kinase inhibition were observed in vivo.
30. They measured the kinase activity using a colorimetric assay.
31. The kinase has been linked to neurodegenerative diseases.
32. The team published their findings on the novel kinase in a scientific journal.
33. The kinase showed specificity for its substrate during the reaction.
34. The role of the kinase in tumor metabolism is currently under investigation.
35. The kinase inhibitors showed potential in reducing tumor size.
36. Scientists are exploring how the kinase is activated in response to stress.
37. The kinase family includes many members with diverse functions.
38. The kinase was found to be a critical regulator of the cell cycle.
39. Their work focused on how the kinase affects cellular signaling.
40. The kinase is crucial for maintaining cellular homeostasis.
41. The kinase was detected in various tissue samples.
42. The team aimed to elucidate the mechanism of the kinase action.
43. The kinase was silenced in the experiment to assess its function.
44. Elevated levels of the kinase were associated with poor prognosis.
45. The kinase phosphorylates both serine and threonine residues.
46. The kinase activity was inhibited by a specific small molecule.
47. The kinase has a pivotal role in the response to DNA damage.
48. Targeting the kinase could provide a new avenue for treatment.
49. The kinase was implicated in the regulation of circadian rhythms.
50. Their goal was to develop a selective kinase inhibitor.
51. The kinase assay revealed unexpected results.
52. The team discovered a novel function of the kinase in immune response.
53. The kinase was found to be involved in lipid metabolism.
54. The kinase signaling pathway is complex and tightly regulated.
55. Researchers are designing compounds that can selectively inhibit the kinase.
56. The kinase plays a central role in growth factor signaling.
57. The kinase is a potential biomarker for certain diseases.
58. The team used CRISPR to knock out the kinase gene.
59. Understanding the kinase interactions is critical for drug design.
60. The kinase has a unique catalytic mechanism.
61. The kinase was overactivated in the diseased tissues.
62. The presence of the kinase was confirmed using Western blotting.
63. The kinase is essential for neuronal development.
64. The kinase inhibitors are showing promise in preclinical studies.
65. The researchers hypothesized that the kinase modulates stress responses.
66. The kinase was identified as a target for antiviral therapy.
67. The kinase cascade amplifies the signal within the cell.
68. Inhibition of the kinase resulted in decreased cell proliferation.
69. The kinase was characterized using mass spectrometry.
70. The kinase plays a role in synaptic plasticity.
71. The study demonstrated that the kinase regulates metabolic pathways.
72. The kinase is essential for proper immune function.
73. The kinase signaling is altered in many cancers.
74. The kinase was found to be upregulated in response to stress.
75. They are screening for small molecules that can inhibit the kinase.
76. The kinase is a key player in cellular communication.
77. The kinase was studied in the context of cardiovascular disease.
78. Understanding how the kinase functions will aid in drug discovery.
79. The kinase family is known for its diverse substrate specificity.
80. The kinase activity was measured using a radiolabeled substrate.
81. The role of the kinase in signal transduction is critical.
82. The kinase was linked to the regulation of apoptosis.
83. The kinase inhibitors are being evaluated for safety and efficacy.
84. The researchers aimed to understand the kinase's role in metabolism.
85. The kinase was involved in the phosphorylation of transcription factors.
86. The kinase is a target for precision medicine approaches.
87. The study provided insights into the kinase's structure and function.
88. The kinase is activated by various extracellular signals.
89. The kinase contributes to cell cycle regulation.
90. The findings suggest that the kinase may have therapeutic potential.
91. The kinase was shown to interact with other signaling molecules.
92. The kinase was implicated in the pathogenesis of the disease.
93. The kinase plays a role in the response to oxidative stress.
94. Researchers are investigating the kinase's role in metabolic syndrome.
95. The kinase was identified as a key regulator of cell growth.
96. The kinase inhibitors are a promising class of therapeutics.
97. The kinase was found to modulate the immune response.
98. The kinase is essential for maintaining cellular integrity.
99. The team is focused on understanding the kinase signaling network.
100. The kinase was shown to have multiple biological functions.