100 Examples of sentences containing the common noun "ligand"

Definition

A ligand is a molecule that binds to another (usually larger) molecule, often a receptor or an enzyme, to form a complex that can initiate a biochemical reaction or signal. In the context of chemistry, ligands can be ions or molecules that coordinate to a central atom, typically a metal, forming a coordination complex.

Synonyms

• Binder
• Connector
• Linker
• Adaptor
• Complexing agent

Antonyms

• Unbinder
• Dissociator
• Separator

Examples

1. The ligand binds with the receptor to trigger a cellular response.
2. Researchers are studying how the ligand interacts with various enzymes.
3. A strong ligand can enhance the efficacy of a drug.
4. The metal ion in the complex requires a suitable ligand for stabilization.
5. Understanding how a ligand behaves in solution is crucial for drug design.
6. The ligand affinity can be measured using various biochemical assays.
7. Scientists discovered a new ligand that shows promise in cancer treatment.
8. The ligand was modified to improve its binding properties.
9. A synthetic ligand can mimic natural substrates in biochemical reactions.
10. The ligand concentration affects the rate of the reaction.
11. In this experiment, we will measure how well the ligand interacts with the target protein.
12. A bioluminescent ligand can provide insights into cellular processes.
13. The ligand dissociates from the receptor after the signaling cascade is complete.
14. This study focuses on a unique ligand that targets a specific type of cancer cell.
15. The ligand plays a critical role in the formation of the complex.
16. A competitive ligand can inhibit the activity of the primary ligand.
17. The research team synthesized a new ligand to improve drug delivery.
18. The binding site on the enzyme is where the ligand attaches.
19. The ligand used in this study was chosen for its high specificity.
20. A change in ligand structure can impact the overall function of the molecule.
21. The ligand was found to stabilize the metal center in the complex.
22. High-throughput screening identified several potential ligands.
23. The ligand forms a temporary bond with the receptor.
24. To evaluate binding strength, we tested various ligands.
25. The ligand was labeled for tracking in live cell imaging.
26. A new class of ligands has emerged in the field of organometallic chemistry.
27. The ligand facilitated the transfer of electrons in the reaction.
28. This novel ligand has unique properties that set it apart from others.
29. The ligand concentration is critical for achieving the desired reaction rate.
30. Understanding the ligand interaction can lead to better therapeutic strategies.
31. The ligand is responsible for the activation of the signaling pathway.
32. We need to optimize the ligand conditions for maximum efficacy.
33. In this study, we focus on the role of a specific ligand in cellular signaling.
34. The ligand bonding affinity was tested through various assays.
35. A weaker ligand may lead to less effective drug action.
36. The ligand can alter the conformation of the target protein.
37. The complex formed by the ligand and receptor is crucial for function.
38. A detailed understanding of the ligand-receptor interaction is necessary for drug development.
39. The ligand was effective in reducing symptoms in the experimental model.
40. We synthesized a library of ligands to explore their binding properties.
41. The ligand was characterized using mass spectrometry.
42. A ligand that can cross the blood-brain barrier is highly sought after in neuroscience.
43. The specific ligand binding can lead to a cascade of cellular events.
44. Researchers are developing ligands that can selectively target cancer cells.
45. The ligand concentration was adjusted to achieve optimal binding.
46. The ligand forms a stable complex with the metal ion.
47. A fluorescent ligand can help visualize molecular interactions.
48. The ligand was identified through a series of biochemical tests.
49. The study revealed that the ligand could enhance receptor activity.
50. The ligand binding site was mapped using X-ray crystallography.
51. The formation of the ligand-protein complex is essential for enzyme function.
52. A new assay was developed to measure ligand binding kinetics.
53. The ligand served as a key component in the catalytic cycle.
54. Structural changes in the ligand can affect its biological activity.
55. The ligand was delivered via a targeted nanocarrier.
56. A stable ligand can improve the bioavailability of the drug.
57. The interaction between the ligand and receptor is highly specific.
58. This ligand can modulate the activity of the target enzyme.
59. The ligand was shown to have low toxicity in preliminary tests.
60. The ligand was designed to selectively bind to the target site.
61. A detailed analysis of the ligand structure revealed important features.
62. The ligand can influence gene expression in certain cell types.
63. The discovery of this ligand opens new avenues for research.
64. The ligand was tested in various biological systems.
65. A potent ligand might lead to the development of a new therapy.
66. Understanding the ligand interactions is vital for designing effective drugs.
67. The ligand was isolated from a natural source for further study.
68. The binding affinity of the ligand was evaluated using surface plasmon resonance.
69. A ligand that increases receptor sensitivity could enhance treatment outcomes.
70. The ligand was successfully synthesized in the laboratory.
71. The ligand was characterized by NMR spectroscopy.
72. A dual-target ligand may provide better therapeutic effects.
73. The ligand plays a pivotal role in cell signaling pathways.
74. The ligand was shown to inhibit the growth of tumor cells.
75. A ligand with a high degree of specificity is essential for effective therapy.
76. The ligand can alter the pharmacokinetics of the drug.
77. The ligand must be carefully selected to avoid off-target effects.
78. The researchers are exploring the potential of a new ligand in immunotherapy.
79. The ligand was visualized using advanced imaging techniques.
80. The binding of the ligand was confirmed through various assays.
81. A ligand with a higher binding constant is preferred in drug development.
82. The ligand was evaluated for its potential side effects.
83. The ligand-receptor interaction is fundamental to the drug's mechanism of action.
84. The study highlighted the importance of the ligand in enzymatic reactions.
85. A ligand that can stabilize a transition state could enhance reaction rates.
86. The ligand was found to have synergistic effects with other compounds.
87. The ligand showed promise in preclinical trials for treating autoimmune diseases.
88. The design of the ligand was based on structure-activity relationship studies.
89. A specific ligand can regulate the activity of transcription factors.
90. The ligand was successfully used in a therapeutic context.
91. A versatile ligand can have applications in multiple fields of research.
92. The ligand was shown to improve the solubility of the drug.
93. A novel ligand design can lead to breakthroughs in medicine.
94. The ligand-metal complex was stable under various conditions.
95. A targeted ligand can reduce the impact of side effects in treatment.
96. The ligand was identified as a key player in cell communication.
97. A promising ligand was discovered during high-throughput screening.
98. The ligand was delivered using a smart drug delivery system.
99. A comprehensive study of the ligand helped elucidate its biological roles.
100. The ligand was an essential factor in the biochemical pathway studied.