100 Examples of sentences containing the common noun "overexpression"

Definition

Overexpression refers to the phenomenon where a gene or protein is produced in excessive amounts beyond the normal levels. This can occur in biological systems due to various factors, including genetic mutations, environmental influences, or experimental manipulations. In a broader context, "overexpression" can also refer to any situation where an idea, emotion, or quality is expressed to an exaggerated degree.

Synonyms

• Hyperexpression
• Excessive expression
• Overproduction
• Amplification

Antonyms

• Underexpression
• Downregulation
• Suppression
• Reduction

Examples

1. Scientists observed that the overexpression of the gene led to increased tumor growth.
2. The overexpression of inflammatory cytokines can cause tissue damage.
3. Researchers are studying the overexpression of certain proteins in cancer cells.
4. The overexpression of this enzyme is crucial for metabolic disorders.
5. In this experiment, we induced the overexpression of the target gene.
6. The overexpression of the growth factor resulted in enhanced cell proliferation.
7. The study highlighted the implications of gene overexpression in developmental biology.
8. Overexpression of this receptor may alter normal signaling pathways.
9. The overexpression of the transcription factor has been linked to autoimmune diseases.
10. Overexpression of the protein was confirmed through Western blot analysis.
11. The results indicated that overexpression negatively affected cell differentiation.
12. An example of overexpression can be seen in certain genetic disorders.
13. The researchers were concerned about the overexpression of the antibiotic resistance gene.
14. Overexpression of the signaling molecule could lead to chronic inflammation.
15. They hypothesized that overexpression of the gene would enhance the protein's function.
16. The overexpression of these markers is often used in diagnostic tests.
17. We are examining the effects of overexpression on cell viability.
18. The overexpression of the oncogene was a key finding in the study.
19. Overexpression of certain genes can disrupt normal cellular homeostasis.
20. The team observed overexpression in response to environmental stressors.
21. Overexpression of this protein is a hallmark of several cancers.
22. The implications of overexpression are significant in gene therapy.
23. Overexpression of the enzyme was linked to metabolic syndrome.
24. The findings suggest that overexpression could be targeted for therapeutic interventions.
25. Overexpression in model organisms provided insights into the gene's function.
26. The researchers noted that overexpression led to unexpected phenotypic changes.
27. Overexpression of the extracellular matrix proteins was observed in fibrotic tissues.
28. The phenomenon of overexpression is critical for understanding gene regulation.
29. Overexpression of this gene in animal models has provided valuable information.
30. The study aimed to investigate the role of overexpression in neurodegenerative diseases.
31. Overexpression of the growth hormone can lead to acromegaly.
32. The team utilized CRISPR technology to induce overexpression in the lab.
33. Overexpression of the protein was evident in the tissue samples.
34. The authors discussed the consequences of overexpression on cellular pathways.
35. In this case, overexpression was induced using viral vectors.
36. Overexpression of the transcriptional repressor was unexpected in this context.
37. The model predicted that overexpression would enhance the therapeutic effect.
38. Overexpression studies have elucidated the pathways involved in cancer progression.
39. Overexpression of the enzyme showed potential for biotechnological applications.
40. The researchers measured the extent of overexpression using quantitative PCR.
41. Overexpression can be a double-edged sword in cellular processes.
42. The overexpression of genes related to stress response was observed.
43. There was significant overexpression in the treated samples compared to the controls.
44. Genetic modifications led to the overexpression of the desired traits.
45. The implications of overexpression are still being explored in various fields.
46. Overexpression of certain genes can lead to metabolic dysregulation.
47. The results demonstrated that overexpression is a key factor in pathogenesis.
48. Overexpression in yeast models provided a platform for functional assays.
49. The overexpression of cytokines is often associated with chronic diseases.
50. Overexpression of several proteins was confirmed by immunofluorescence.
51. The implications of gene overexpression are profound in cancer research.
52. The researchers were surprised by the overexpression of the suppressor gene.
53. Overexpression of the protein caused a significant increase in cellular activity.
54. The study focused on the overexpression of genes linked to inflammation.
55. Overexpression has been linked to enhanced drug resistance in some cases.
56. They aimed to characterize the effects of overexpression on cell signaling.
57. The experiment demonstrated that overexpression could lead to cell cycle disruption.
58. The overexpression of specific genes was crucial for the study's conclusions.
59. Inhibition of overexpression may be a potential therapeutic strategy.
60. The observed overexpression in the model organism was striking.
61. Overexpression can complicate the interpretation of results in experiments.
62. The overexpression of certain proteins is a common feature of oncogenesis.
63. Overexpression of the target genes was verified through various assays.
64. The overexpression of this gene has implications for evolutionary biology.
65. The findings indicate that overexpression may be a response to stress.
66. Overexpression of certain factors can lead to physiological changes.
67. The team aimed to suppress overexpression to restore normal function.
68. The overexpression of the receptor was linked to increased sensitivity to the drug.
69. The researchers discussed how overexpression could impact gene therapy approaches.
70. Overexpression may serve as a biomarker for disease progression.
71. The overexpression of proteins was evident in the experimental group.
72. They hypothesized that overexpression would enhance therapeutic efficacy.
73. Overexpression of this protein can lead to adverse effects in patients.
74. The implications of overexpression extend beyond cancer research.
75. Overexpression can be induced through genetic engineering techniques.
76. The study demonstrated that overexpression of the gene altered metabolic pathways.
77. Overexpression was detected during the early stages of tumor development.
78. The overexpression of enzymes can affect metabolic flux.
79. The researchers focused on the overexpression of the signaling proteins.
80. They aimed to mitigate the effects of overexpression in their experiments.
81. Overexpression of this gene has been linked to various health conditions.
82. The overexpression of certain genes can lead to cellular dysfunction.
83. The study provided insights into the mechanisms behind overexpression.
84. Overexpression of this factor was observed in response to stress stimuli.
85. The team aimed to characterize the pathways involved in overexpression.
86. Overexpression of the gene was found to correlate with disease severity.
87. The overexpression of inflammatory mediators can exacerbate conditions.
88. Researchers are looking into the role of overexpression in cell signaling.
89. The phenomenon of overexpression has broad implications in research.
90. The overexpression of the transcription factor was confirmed through assays.
91. Overexpression of key proteins was integral to the study's findings.
92. The researchers speculated on the role of overexpression in development.
93. Overexpression can result in a loss of normal regulatory mechanisms.
94. The overexpression of this gene has been implicated in several diseases.
95. The findings revealed that overexpression could lead to adverse side effects.
96. Overexpression of certain cytokines was a hallmark of the disease model.
97. The implications of overexpression are significant for therapeutic strategies.
98. The overexpression of genes can provide insights into cellular behavior.
99. They measured the levels of overexpression using various techniques.
100. The study highlighted the need to understand the consequences of overexpression.