100 Examples of sentences containing the common noun "substituent"

Definition

A substituent refers to an atom or group of atoms that replaces another atom or group of atoms in a chemical compound. It is commonly used in organic chemistry to describe functional groups that can be attached to a parent hydrocarbon chain, altering its properties and reactivity.

Synonyms

• Substituent group
• Functional group
• Replacing group
• Modifier
• Additive

Antonyms

• Parent compound
• Original group
• Base structure

Examples

1. The chemist introduced a new substituent to the molecule.
2. When a substituent is added to the ring structure, the stability may change.
3. A methyl substituent can significantly influence the boiling point of the compound.
4. Different substituents can lead to variations in chemical properties.
5. The study focused on how each substituent affected the reactivity of the compound.
6. An electron-withdrawing substituent can increase acidity.
7. The presence of a bulky substituent can hinder reactions.
8. A chlorine substituent was found to enhance solubility in water.
9. Researchers analyzed the effect of each substituent on the compound's behavior.
10. The compound contained multiple substituents that altered its stability.
11. The introduction of a nitro substituent changed the compound's color.
12. Each substituent was systematically evaluated for its impact.
13. A simple substituent can make the molecule more reactive.
14. The substituent influenced the overall molecular geometry.
15. By modifying the substituent, the reaction rate increased dramatically.
16. The presence of a hydroxyl substituent is crucial for biological activity.
17. A branched substituent can create steric hindrance in the molecule.
18. The researchers synthesized several compounds with different substituents.
19. A substituent at the meta position can have distinct effects compared to the ortho position.
20. The choice of substituent determines the compound's pharmacological profile.
21. They discovered that adding a sulfur substituent enhanced the compound's efficacy.
22. Each substituent was carefully chosen for its desired chemical properties.
23. The substituent groups were identified using spectroscopic techniques.
24. The effect of the substituent on the equilibrium constant was remarkable.
25. The analysis revealed that the substituent affected the compound's reactivity.
26. A unique substituent can lead to the discovery of new pharmaceuticals.
27. The substituent was pivotal in designing the new synthetic pathway.
28. The interaction between the substituent and the solvent was studied in depth.
29. The researchers noted that the substituent could influence intermolecular forces.
30. Each substituent was accounted for in the reaction mechanism.
31. The substituent contributed to the overall polarity of the molecule.
32. A smaller substituent might allow for better packing in the crystal lattice.
33. The data showed that the substituent had a significant impact on enzyme activity.
34. They hypothesized that the substituent would alter the compound's stability.
35. The substituent acted as a catalyst in the reaction.
36. By replacing the existing substituent, they improved the compound's yield.
37. The substituent was crucial for the binding affinity of the drug.
38. The presence of a keto substituent can stabilize the molecule.
39. The substituents on the aromatic ring were thoroughly examined.
40. A substituent can enhance the solubility of the compound in organic solvents.
41. The substituent was identified as a key factor in the reaction's success.
42. Structural analysis revealed that the substituent influenced the compound's geometry.
43. The researchers synthesized a new compound with a complex substituent.
44. The stability of the product was influenced by the substituent present.
45. The substituent was effective in modifying the compound's reactivity.
46. A substituent can be as simple as a hydrogen atom or as complex as a whole functional group.
47. The researchers experimented with various substituents to find an optimal solution.
48. The substituent caused unexpected changes in the reaction mechanism.
49. They explored how the substituent affected the rate of reaction.
50. The effects of the substituent were documented in their research findings.
51. The presence of a polar substituent can lead to hydrogen bonding.
52. The substituent proved to be essential for the compound's activity.
53. The team was interested in how the substituent would affect solubility.
54. A substituent at the terminal position can significantly alter the compound's properties.
55. The substituent interacted with the active site of the enzyme.
56. They noted that the substituent could stabilize transient states in the reaction.
57. The influence of the substituent on the electronic properties was profound.
58. A new substituent was introduced to test its effects on the compound.
59. The role of the substituent in the reaction pathway was elucidated.
60. The molecular model demonstrated how the substituent fit within the structure.
61. The substituent was essential for achieving the desired chemical transformation.
62. The impact of the substituent on the overall reaction yield was significant.
63. They found that the substituent could enhance the selectivity of the reaction.
64. The study concluded that the substituent played a critical role in the mechanism.
65. The substituent was carefully analyzed for its steric and electronic effects.
66. The findings highlighted the importance of the substituent in drug design.
67. The substituent was identified as a potential target for modification.
68. A substituent can dramatically change the physical properties of a compound.
69. The research focused on the relationship between the substituent and reactivity.
70. They assessed how different substituents impacted the compound's behavior.
71. The substituent was attached via a nucleophilic substitution reaction.
72. The effects of the substituent were consistent across multiple experiments.
73. A novel substituent was synthesized to test its biological activity.
74. The substituent contributed to the overall lipophilicity of the molecule.
75. The introduction of a halogen substituent changed the reaction profile.
76. Each substituent was evaluated for its contribution to the compound's effectiveness.
77. The substituent altered the compound's electronic distribution.
78. A simple change in the substituent can lead to vastly different outcomes.
79. The team was excited to discover how the substituent interacted with the target.
80. The substituent was crucial for the binding interaction.
81. The results demonstrated that the substituent had a significant effect on the reaction.
82. Researchers were intrigued by the properties of the new substituent.
83. A substituent can modify the reactivity of the parent compound.
84. The substituent was attributed to the unique properties of the compound.
85. The study involved a detailed examination of the substituent effects.
86. The substituent was essential for improving the selectivity of the reaction.
87. Variations in the substituent were found to impact the compound's performance.
88. The substituent demonstrated potential as a new lead compound.
89. The substituent was analyzed to understand its contribution to stability.
90. A different substituent was hypothesized to enhance activity.
91. The impact of the substituent on molecular interactions was explored.
92. The substituent could be modified to optimize the compound's properties.
93. Each substituent was considered in the context of the overall molecular design.
94. The substituent was integral to the compound's bioactivity.
95. The results indicated that the substituent affected the reaction kinetics.
96. The substituent was identified through careful spectroscopic analysis.
97. The presence of a vinyl substituent can lead to unique reactivity patterns.
98. The substituent was shown to influence the compound's solubility.
99. A thorough understanding of the substituent is essential for predicting behavior.
100. The findings emphasized the role of the substituent in the overall chemical landscape.